Thèse - PHD THESIS CEMEF 2021 : Bio-aerogels for Biomedical Applications Using Additive Manufacturing and Numerical Simulation

Description :
Presentation of the establishment and the laboratory of reception :
CEMEF, which stands for Centre de Mise en Forme des Matériaux, or Centre for Material Forming, is a leading research centre in the field of material forming. It was created in 1974 and is located in the Sophia Antipolis science park, near Nice in the south of France. It is a research laboratory of Mines ParisTech and has been associated with CNRS, the French National Science Foundation since 1979.
CEMEF develops global approaches in material forming (polymers, bio-polymers, elastomers, metals, alloys...), combining physics, physical chemistry, mechanics, thermics, modelling, numerical simulation (finite element methods, meshing, fluid-structure coupling...). The scientific developments are applied to forming processes : injection molding, extrusion, forging, machining, rolling, welding... It has about 160 people, including 70 PhD students.

Thesis work description :
Bio-aerogels are emerging class of bio-based materials ; they are nanostructured and highly porous. In our laboratory we develop aerogels based on polysaccharides which are very promising materials for life science applications. In this work new bio-aerogels will be developed combining controlled meso- and macroporosity, on-demand shape, controlled release of drugs and absorption of excess blood, plasma and other fluids. The analyses will be conducted through a mixed approach combining experiments, modelling and 3D numerical simulations.
The bio-aerogels will be prepared from cellulose based polymers, which are used in biomedical field. These polysaccharide solutions will be printed and transformed into bio-aerogels. 3D printing experimental work will be accompanied by non-Newtonian fluid mechanics modelling and 3D numerical simulations in order to understand shaping and predict the best printing conditions.

The bio-aerogels will be prepared from cellulose based polymers, which are used in biomedical field. These polysaccharide solutions will be printed and transformed into bio-aerogels. 3D printing experimental work will be accompanied by non-Newtonian fluid mechanics modelling and 3D numerical simulations in order to understand shaping and predict the best printing conditions.

Skills required :
Knowledge in materials science, polymer chemistry & polymer physics and numerical modelling ; fluent in English, highly motivated, pro-active ; MSc thesis completed

More detail on :
https://www.cemef.minesparis.psl.eu...

Application online only : fill in the form on line : https://applyfor.cemef.mines-parist...

The deadline for applications is June 15th 2021

Reference : BioAeroSim

Date de démarrage : 04 octobre 2021

Durée : 3 ans

Contacter :
MINES ParisTech - CEMEF
Dr. Tatiana Budtova
MINES ParisTech - CEMEF 1, rue Claude Daunesse 06560 Valbonne-Sophia antipolis
email : tatiana.budtova@mines-paristech.fr
Téléphone : 0493957470

Page web : https://www.cemef.minesparis.psl.eu/